Sample Essay

In vitro and in vivo data have demonstrated that Bispecific antibodies offer the potential to improve the therapeutic efficacy of antibodies, which rely on efficient effector cell recruitment as relevant mechanisms of action. Results from clinical trials with Bispecific antibodies, however, are less encouraging. As explanations for these disappointing clinical results are provided by analyses of the available data, genetic engineering offers rational approaches for improved second-generation constructs.

Thus, novel Bispecific antibodies may emerge as a promising approach to enhance the therapeutic efficacy of antibody constructs as the antibody market becomes more competitive over the next few years.  These approaches are all having their own advantages and disadvantages but progress only occurs when considering the advantages which might be significantly less compare to the disadvantages are taken in consideration and research continues. The initiative was taken with an intention to treat oncological problems but with new explorations during experimentation made it evident that for a number of autoimmune diseases this will be the same beneficial act as for cancers.

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